Let's see...
The first thing i noticed is the right leg looks extremely awkward. It looks very uhhh... limp? and the prospective on the foot all the way to the knee is off as well.
The eyes look a bit strange for this style, but there is nothing wrong with them, just not my style.
The last few things are her hips look too low and long, her breast a bit low as well, and her left hand looks more like a paw than a hand.
Now, to how you can fix these things. From what i've seen, you are pretty far into the rendering and i doubt you will go back to change some major stuff, like the legs, hips, and whatnot. But if you can, and want to, i would, it would make this piece a whole lot better. Though i do think you can fix the hand easily, and would be a good investment of time.
Check out this tut for drawing hands:
https://www.youtube.com/watch?v=qUbt1l4tBJg
Everything else is great though, the pose is exciting, the clothing design is pretty cool too.