An apocalyptic reading of Jenkins's hypothesis has that, when the galactic alignment occurs, it will somehow create a combined gravitational effect between the Sun and the supermassive black hole at the center of our galaxy (known as Sgr A*), creating havoc on Earth.[68] Apart from the fact noted above that the "galactic alignment" predicted by Jenkins already happened in 1998, the Sun's apparent path through the zodiac as seen from Earth does not take it near the true galactic center, but rather several degrees above it.[69] Even if this were not the case, Sgr A* is 30,000 light years from Earth, and would have to be more than 6 million times closer to cause any gravitational disruption to Earth's Solar System.[70][71]

Some versions of this idea associate the theory of a 2012 "galactic alignment" with that of a very different "galactic alignment" proposed by some scientists to explain a supposed periodicity in mass extinctions in the fossil record.[72] The hypothesis supposes that vertical oscillations made by the Sun as it orbits the galactic center cause it to regularly pass through the galactic plane. When the Sun's orbit takes it outside the galactic disc, the influence of the galactic tide is weaker; as it re-enters the galactic disc, as it does every 20–25 million years, it comes under the influence of the far stronger "disc tides", which, according to mathematical models, increase the flux of Oort cloud comets into the Solar System by a factor of 4, leading to a massive increase in the likelihood of a devastating comet impact.[73] However, this "alignment" takes place over tens of millions of years, and could never be timed to an exact date.[74] Evidence shows that the Sun passed through the galactic disc only three million years ago, and is now moving farther above it.[75]