Shaders should stay on after you quit the game, but the specific shader you've loaded doesn't. If the former isn't happening, then I'm sure there's a shortcut extension you could use or something that will automatically load shaders for you, but I don't know what it is. Perhaps when Stilf comes online he'll be able to tell you, or someone else will.
"Call yourself alive? I promise you you'll be deafened by dust falling on the furniture,
you'll feel your eyebrows turning to two gashes, and your shoulder blades will ache for want of wings."